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Contents and Lead Article

Contents
- Adherence with self-administered treatment of latent tuberculosis infection in Auckland
- Molecular subtyping links geographically separate shigellosis outbreaks
- Sexually transmitted infections in 2000
- Surveillance and control notes
Lead Article:
Adherence with self-administered treatment of latent tuberculosis infection in Auckland
The aims of this study were to determine the level of adherence to
self-administered treatment of latent tuberculosis infection with
isoniazid, client understanding of treatment and their knowledge of the
symptoms and signs of hepatotoxicity. Seventy-six people were
interviewed. Findings included a high level of understanding of the
drug regimen and reasons for treatment, a high level of adherence
(compared to other studies) ranging from 72% to 89% (using various
definitions of adherence) and a low level of knowledge of the side
effects of isoniazid. Clinicians prescribing treatment of latent
tuberculosis infection should be alert to the possibility of
non-adherence, ensure client understanding of the signs and symptoms of
hepatitis and inform the clients general practitioner when treatment is
commenced.
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